| Identification | Back Directory | [Name]
(R)-BPO-27 | [CAS]
1415390-47-4 | [Synonyms]
BPO-27
(R)-BPO-27
6H-Pyrimido[4',5':3,4]pyrrolo[2,1-c][1,4]benzoxazine-2-carboxylic acid, 6-(5-bromo-2-furanyl)-7,8,9,10-tetrahydro-7,9-dimethyl-8,10-dioxo-11-phenyl-, (6R)-
BENZOPYRIMIDO-PYRROLO-OXAZINEDIONE BPO-27 [6-(5-BROMOFURAN-2-YL)-7,9-DIMETHYL-8,10-DIOXO- 11-PHENYL-7,8,9,10-TETRAHYDRO-6H-BENZO[B]PYRIMIDO [49,59: 3,4]PYRROLO [1,2-D][1,4]OXAZINE-2-CARBOXYLIC ACID] | [Molecular Formula]
C26H18BrN3O6 | [MDL Number]
MFCD30532675 | [MOL File]
1415390-47-4.mol | [Molecular Weight]
548.34 |
| Chemical Properties | Back Directory | [Boiling point ]
732.9±70.0 °C(Predicted) | [density ]
1.68±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:14.28(Max Conc. mg/mL);26.04(Max Conc. mM) | [form ]
Solid | [pka]
3.76±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
BPO-27 is a potent and metabolically stable CFTR inhibitor. | [target]
(R)-BPO-27, the R enantiomer of BPO-27, is a potent, orally active and ATP-competitive CFTR inhibitor with an IC50 of 4 nM. | [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
|