ChemicalBook--->CAS DataBase List--->1415558-82-5

1415558-82-5

1415558-82-5 Structure

1415558-82-5 Structure
IdentificationBack Directory
[Name]

2-Keto Crizotinib
[CAS]

1415558-82-5
[Synonyms]

PF-06260182
2-Keto Crizotinib
Crizotinib impurity B
Crizotinib 2-Keto Impurity
KLXFBZLBBBMWAI-YNODCEANSA-N
Crizotinib metabolite hydrochloride salt
2-Piperidinone, 4-[4-[6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-pyridinyl]-1H-pyrazol-1-yl]-
[Molecular Formula]

C21H20Cl2FN5O2
[MDL Number]

MFCD22124891
[MOL File]

1415558-82-5.mol
[Molecular Weight]

464.32
Chemical PropertiesBack Directory
[Boiling point ]

679.9±55.0 °C(Predicted)
[density ]

1.53±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

15.68±0.40(Predicted)
[color ]

Pale Beige to Light Beige
Hazard InformationBack Directory
[Uses]

2-Keto Crizotinib is an impurity of Crizotinib (C785000), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.
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