| Identification | Back Directory | [Name]
N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine | [CAS]
1421372-94-2 | [Synonyms]
AZD9291 1
EOS-61221
AZD9291 N-3
AZD9291 Intermediate 2
OSIMERTINIB INTERMEDIATE 1
Osimertinib mesylate intermediate 1
N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-3-indolyl)-2-pyrimidinamine
N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine
N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine
N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine
2-PyriMidinaMine, N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methyl-1H-indol-3-yl)-
(4-Fluoro-2-methoxy-5-nitro-phenyl)-[4-(1-methyl-1h-indol-3-yl)-pyrimidin-2-yl]-amine
N-(4-fluoro-2-methoxy-5-nitrophenyl)-
4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) | [EINECS(EC#)]
806-156-3 | [Molecular Formula]
C20H16FN5O3 | [MDL Number]
MFCD28167946 | [MOL File]
1421372-94-2.mol | [Molecular Weight]
393.37 |
| Chemical Properties | Back Directory | [Melting point ]
>250°C (dec.) | [Boiling point ]
639.3±65.0 °C(Predicted) | [density ]
1.41±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
DMSO (Slightly, Heated) | [form ]
Solid | [pka]
2.02±0.10(Predicted) | [color ]
Light Yellow to Yellow |
| Hazard Information | Back Directory | [Uses]
N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine functions as a reagent in the synthesis of dihydropyrroloquinoline derivatives with anticancer activity as EGFR modulator to inhibit L858R/T790M. |
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