| Identification | Back Directory | [Name]
Oxyphenonium | [CAS]
14214-84-7 | [Synonyms]
Diethylmethyl[2-(hydroxyphenylcyclohexylacetoxy)ethyl]aminium
2-[Cyclohexyl(hydroxy)(phenyl)acetoxy]-N,N-diethyl-N-methylethanaminium | [Molecular Formula]
C21H34NO3+ | [MOL File]
14214-84-7.mol | [Molecular Weight]
348.51 |
| Hazard Information | Back Directory | [Originator]
A-Spasm ,Acme Laboratories Ltd. | [Definition]
ChEBI: 2-(2-cyclohexyl-2-hydroxy-1-oxo-2-phenylethoxy)ethyl-diethyl-methylammonium is an acylcholine. | [Manufacturing Process]
1 mol cycloxehylhydroxyphenylacetic acid methyl ester was mixed with 1 mol 2-diethylaminoethanol in presence of 1 mol sodium methylate to give cycloxehylhydroxyphenylacetic acid 2-diethylamino-ethyl ester.
5 parts by weight of it was dissolved in 50 volumes glacial acetic acid and a gaseous methyl bromide was introduced. The mixture was heated to about 50°C and crystallization of cycloxehylhydroxyphenylacetic acid diethylaminoethyl ester methyl bromide has shortly after begun. On cooling the crystals was filtered off and recrystallized from mixture of ethyl acetate ant a little ethanol to give the oxyphenonium bromide. MP: 189°-191°C.
| [Brand name]
Antrenyl (Novartis). | [Therapeutic Function]
Anticholinergic, Spasmolytic |
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