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142720-24-9

142720-24-9 Structure

142720-24-9 Structure
IdentificationBack Directory
[Name]

FGIN-1-27
[CAS]

142720-24-9
[Synonyms]

FGIN-1-27
FGIN-1-27,98%
N,N-DIHEXYL-2-(4-FLUOROPHENYL)INDOLE-3-ACETAMIDE
N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide
FGIN-1-27N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide
[Molecular Formula]

C28H37FN2O
[MDL Number]

MFCD00467704
[MOL File]

142720-24-9.mol
[Molecular Weight]

436.6
Chemical PropertiesBack Directory
[Appearance]

white to off-white powder
[Melting point ]

96-97 °C
[Boiling point ]

608.3±55.0 °C(Predicted)
[density ]

1.0538 (estimate)
[storage temp. ]

2-8°C
[solubility ]

methanol: 20 mg/mL
[form ]

White powder.
[pka]

16.45±0.30(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Chemical Properties]

white to off-white powder
[Biological Activity]

Binds specifically and with high affinity to the peptide DBI receptor (benzodiazepine receptor) on mitochondrial membranes, inducing production of neurosteroids, which modulate GABA receptors (EC 50 = 3 nM for increase in production of pregnenolone in glial cells). Thus it reduces anxiety without causing sedation.
[Uses]

FGIN-1-27 is a potent inositol monophosphatase inhibitor.
[Definition]

ChEBI: 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide is a phenylindole.
[storage]

Room temperature
Safety DataBack Directory
[Safety Statements ]

24/25
[WGK Germany ]

3
[HS Code ]

29339980
Spectrum DetailBack Directory
[Spectrum Detail]

FGIN-1-27(142720-24-9)1HNMR
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