| Identification | Back Directory | [Name]
JWH 210 N-(4-hydroxypentyl) metabolite | [CAS]
1427521-37-6 | [Synonyms]
JWH 210 N-(4-hydroxypentyl) metabolite
(4-ethylnaphthalen-1-yl)-[1-(4-hydroxypentyl)indol-3-yl]methanone | [Molecular Formula]
C26H27NO2 | [MOL File]
1427521-37-6.mol | [Molecular Weight]
385.5 |
| Hazard Information | Back Directory | [Description]
JWH 210 is a potent cannabimimetic alkylindole that has been identified in extracts from herbal blends. Structurally and functionally similar alkylindoles are rapidly metabolized by the liver and secreted in the urine, with hydroxylation of the alkyl side chain occurring in the liver.1,2,3 JWH 210 N-(4-hydroxypentyl) metabolite is an expected metabolite of JWH 210, detectable in the serum and urine. Its biological activities have yet to be determined. | [References]
1. Teske, J., Weller, J.P., Fieguth, A., et al. Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in human serum by liquid chromatography-tandem mass spectrometry J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 878(27),2659-2663(2010).
2. Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine Forensic Sci. Int. 200(1-3),141-147(2010).
3. Wintermeyer, A., M?ller, I., Thevis, M., et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018 Anal. Bioanal. Chem. 398(5),2141-2153(2010). |
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