| Identification | Back Directory | [Name]
N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite | [CAS]
142808-44-4 | [Synonyms]
DMTr-2’,2’-di fluoro-dC(Bz)-3’-CED-phosphoramidite
N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluoro-2'-deoxycytidine
5'-O-DMT-N4-Benzoyl-2',2'-difluoro-2'-deoxycytidine 3'-CE phosphoramidite
N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite
N4-Benzoyl-5’-O-(4,4’-dimethoxy trityl) -2’,2’-difluoro-2’-deoxycytidine 3’-O-[(2-cyanoethyl) (N,N-diisopropyl)]-phosphoramidite
Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2',2'-difluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] | [Molecular Formula]
C46H50F2N5O8P | [MOL File]
142808-44-4.mol | [Molecular Weight]
869.89 |
| Hazard Information | Back Directory | [Uses]
N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. | [Synthesis]
 1.Dissolve 5'-Dimethoxytrityl-N 4-benzoyl-2',2'-difluoro-2'-deoxycytidine (1 equiv., 0.4 mmol, 270 mg)in anhydrous acetonitrile (6 ml).
2.Add 0.5 M solution of ethylothiotetrazole (1.6 equiv., 0.65 mM, 1.3 ml) in anhydrous acetonitrile and 2-cyanoethyl-bis-(N,N'-diisopropropyl)phosphoramidite (1.43 equiv., 0.57 mmol, 0.2 ml) to the above solution.
3.Stir the reaction mixture at room temperature for 1 h to obtain product. |
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