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143691-37-6

143691-37-6 Structure

143691-37-6 Structure
IdentificationBack Directory
[Name]

GYKI 53405
[CAS]

143691-37-6
[Synonyms]

LY 293606
GYKI 53405
1-[5-(4-aminophenyl)-8-methyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-7-yl]ethanone
Ethanone, 1-[5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-7-yl]-
[Molecular Formula]

C19H19N3O3
[MDL Number]

MFCD09475604
[MOL File]

143691-37-6.mol
[Molecular Weight]

337.37
Safety DataBack Directory
[Symbol(GHS) ]


GHS09,GHS06
[Signal word ]

Danger
[Hazard statements ]

H410-H301
[Precautionary statements ]

P264-P270-P301+P310-P321-P330-P405-P501-P273-P391-P501
Hazard InformationBack Directory
[Description]

GYKI-53405, also known as LY 293606, is a noncompetitive AMPA receptor antagonist. GYKI-53405 binds specifically to Xenopus brain membranes with KD and Bmax values of 4.5 microM and 35 pmol mg-1 protein respectively. Binding is increased in the presence of Mg2+ and is unaffected by AMPA or kainate.
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