| Identification | Back Directory | [Name]
N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanyl-(2S)-2-hydroxy-3-methylbutanoic acid hydrate | [CAS]
144678-63-7 | [Synonyms]
NSC 668036
NSC 668036 hydrate
NSC668036,NSC 668036
N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanine-(1S)-1-carboxy-2-methylpropyl ester
N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-Alanine-(1S)-1-carboxy-2-methylpropyl ester hydrate
N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanyl-(2S)-2-hydroxy-3-methylbutanoic acid hydrate | [Molecular Formula]
C21H36N2O9 | [MDL Number]
MFCD30536365 | [MOL File]
144678-63-7.mol | [Molecular Weight]
460.52 |
| Hazard Information | Back Directory | [Uses]
NSC 668036 hydrate may be used in Wnt-mediated cell signaling studies. | [Biochem/physiol Actions]
NSC 668036 binds to the PDZ domain of the Wnt-pathway signaling molecule Disheveled (Dvl), blocking the binding and activation of Dvl by Frizzled. In Xenopus embryos, NSC 668036 inhibited Wnt3A-induced expression of the target gene Siamois and formation of secondary axes. | [storage]
Store at -20°C |
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