| Identification | Back Directory | [Name]
N-(4-CHLOROBENZYL)-S-[3-(4(5)-IMIDAZOLYL)PROPYL]ISOTHIOUREA | [CAS]
145231-35-2 | [Synonyms]
Clobenpropit (hydrobromide)
Clobenpropit dihydrobromide Solution, 100ppm
Clobenpropit dihydrobromide Solution, 1000ppm
3-(1H-Imidazol-4-yl)propyl 4-Chlorobenzylcarbamimidothioate Dihydrobromide
Apoptosis,inhibit,Clobenpropit dihydrobromide,histamine H3R,antagonist,inverse,Inhibitor,pancreatic,agonist,cancer,H3LR,Histamine Receptor | [Molecular Formula]
C14H17ClN4S.2BrH | [MDL Number]
MFCD00467655 | [MOL File]
145231-35-2.mol | [Molecular Weight]
470.659 |
| Chemical Properties | Back Directory | [Melting point ]
205°C(lit.) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 30 mg/ml; Ethanol: 2.5 mg/ml; Water: 20 mg/ml | [form ]
powder to crystal | [color ]
White to Gray to Red | [Water Solubility ]
Soluble to 100 mM in water |
| Hazard Information | Back Directory | [Uses]
Clobenpropit Dihydrobromide and it’s analogues functions as potent histamine H3 antagonist. | [Definition]
ChEBI: A hydrobromide salt obtained by reaction of clobenpropit with two equivalents of hydrobromic acid. An extremely potent histamine H3 antagonist/inverse agonist (pA2 = 9.93). Also displays partial agonist activity at
H4 receptors; induces eosinophil shape change with an EC50 of 3 nM. | [storage]
Store at RT |
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