ChemicalBook--->CAS DataBase List--->145416-34-8

145416-34-8

145416-34-8 Structure

145416-34-8 Structure
IdentificationBack Directory
[Name]

2-epi-(-)-EMtricitabine
[CAS]

145416-34-8
[Synonyms]

(2S,5S)-Emtricitabine
2-epi-(-)-EMtricitabine
Emtricitabine Impurity 19
Emtricitabine IP Impurity J
Emtricitabine – Enantiomer Impurity
Emtricitabine IP Impurity J (2-epi-Emtricitabine)
4-AMino-5-fluoro-1-[(2S,5S)-2-hydroxyMethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyriMidinone
(2S-trans)-4-AMino-5-fluoro-1-[2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]- 2(1H)-pyriMidinone
2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2S-trans)- (9CI)
Emtricitabine impurity 1/2-epi Emtricitabine/4-amino-5 fluoro-1-[(2S,5S)-2-hydroxymethyl)-1,3-oxathiolane-5-yl]pyrimidin-2(1H)-one
[Molecular Formula]

C8H10FN3O3S
[MDL Number]

MFCD00870151
[MOL File]

145416-34-8.mol
[Molecular Weight]

247.247
Chemical PropertiesBack Directory
[Melting point ]

166-173°C
[Boiling point ]

443.3±55.0 °C(Predicted)
[density ]

1.82±0.1 g/cm3(Predicted)
[storage temp. ]

Refrigerator
[solubility ]

DMSO (Sparingly, Heated), Methanol (Slightly)
[form ]

Solid
[pka]

13.83±0.10(Predicted)
[color ]

Off-White to Light Beige
Hazard InformationBack Directory
[Uses]

The 2-epi-enantiomer analogue of (-)-Emtricitabine (E525000) evaluated against HIV-1 in human peripheral blood mononuclear (PBM) cells.
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