| Identification | Back Directory | [Name]
Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- | [CAS]
1454902-97-6 | [Synonyms]
Elevenostat
N-hydroxy-4-((3-(2-methoxyphenyl)ureido)methyl)benzamide
Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- | [Molecular Formula]
C16H17N3O4 | [MOL File]
1454902-97-6.mol | [Molecular Weight]
315.32 |
| Chemical Properties | Back Directory | [density ]
1.328±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 250 mg/mL (792.85 mM; Need ultrasonic) | [form ]
Solid | [pka]
8.92±0.10(Predicted) | [color ]
Off-white to pink |
| Hazard Information | Back Directory | [Biological Activity]
Elevenostat (JB3-22) is a selective HDAC11 inhibitor (IC50=0.235 μM). Anti-multiple myeloma (MM) activity[1]. | [storage]
Store at -20°C | [References]
[1]. Huang J, et al. Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function. Sci Rep. 2017;7(1):8626. Published 2017 Aug 17.
[2]. Mostofa A, et al. Plasma cell dependence on histone/protein deacetylase 11 reveals a therapeutic target in multiple myeloma. JCI Insight. 2021;6(24):e151713. Published 2021 Dec 22. |
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DC Chemicals
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021-58447131 13564518121 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
InvivoChem
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13549236410 |
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https://www.invivochem.cn/ |
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