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145858-50-0

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145858-50-0 Structure

145858-50-0 Structure
IdentificationBack Directory
[Name]

5-[(3-CHLOROPHENYL)-1H-IMIDAZOL-1-YLMETHYL]-1H-BENZIMIDAZOLE HYDROCHLORIDE
[CAS]

145858-50-0
[Synonyms]

R75251
R-75251
R 75251
Liarozole HCl
Liarozole dihydrochl
LIAROZOLE HYDROCHLORIDE
5-[(3-CHLOROPHENYL)-1H-IMIDAZOL-1-YLMETHYL]-1H-BENZIMIDAZOLE HYDROCHLORIDE
[Molecular Formula]

C17H14Cl2N4
[MDL Number]

MFCD00879803
[MOL File]

145858-50-0.mol
Chemical PropertiesBack Directory
[storage temp. ]

Store at +4°C
Hazard InformationBack Directory
[Uses]

Antineoplastic.
[Uses]

Liarozole Hydrochloride is a Imidazole-containing compound that inhibits the cytochrome P450-dependent metabolism.
[Biological Activity]

Cytochrome P450 inhibitor. Inhibits several cytochrome P450 enzymes including aromatase (CYP19) and retinoic acid 4-hydroxylase (CYP26). Blocks retinoic acid metabolism (retinoic acid metabolism blocking agent, RAMBA). Displays antitumor activity against androgen-dependent and independent rat prostate carcinomas.
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