| Identification | Back Directory | [Name]
Cyclo(D-Phe-Pro-Phe-D-Phe-Asn-Gln-Tyr-Val-Orn-Leu-) | [CAS]
1481-70-5 | [Synonyms]
Tyrocidine A
Cyclo(D-Phe-Pro-Phe-D-Phe-Asn-Gln-Tyr-Val-Orn-Leu-)
Cyclo[L-Asn-L-Gln-L-Tyr-L-Val-L-Orn-L-Leu-D-Phe-L-Pro-L-Phe-D-Phe-]
Cyclo(L-asparaginyl-L-glutaminyl-L-tyrosyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-phenylalanyl-D-phenylalanyl) | [Molecular Formula]
C66H87N13O13 | [MOL File]
1481-70-5.mol | [Molecular Weight]
1270.5 |
| Hazard Information | Back Directory | [Definition]
ChEBI: Tyrocidine A is a homodetic cyclic decapeptide consisting of D-Phe, L-Pro, L-Phe, D-Phe, L-Asn, L-Gln, L-Tyr, L-Val, L-Orn, and L-Leu residues coupled in sequence and cyclised head-to-tail. It has a role as an antibacterial agent and a bacterial metabolite. It is a homodetic cyclic peptide, a peptide antibiotic and a macrocycle. | [Purification Methods]
Crystallise tyrocidine A as the hydrochloride from MeOH or EtOH/HCl. [Paladin & Craig J Am Chem Soc 76 688 1954, King & Craig J Am Chem Soc 77 6624 1955, Okamoto et al. Bull Chem Soc Jpn 50 231 1977, Beilstein 26 III/IV 4280.] |
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