ChemicalBook--->CAS DataBase List--->148229-79-2

148229-79-2

148229-79-2 Structure

148229-79-2 Structure
IdentificationBack Directory
[Name]

(-)-TRAMADOL, HYDROCHLORIDE
[CAS]

148229-79-2
[Synonyms]

E 381
(-)-(1S,2S)-TRAMADOL HCL
(-)-(1S,2S)-Tramadol hydrochloride
(-)-2-[(DIMETHYLAMINO)METHYL]-1-(3-METHOXYPHENYL)CYCLOHEXANOL, HYDROCHLORIDE
(1S-cis)-2-[(DiMethylaMino)Methyl]-1-(3-Methoxyphenyl)cyclohexanol Hydrochloride
(1S,2S)-(-)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol Hydrochloride
[Molecular Formula]

C16H26ClNO2
[MDL Number]

MFCD03701239
[MOL File]

148229-79-2.mol
[Molecular Weight]

299.84
Chemical PropertiesBack Directory
[Appearance]

White Solid
[Melting point ]

171-172°C
[storage temp. ]

Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

An analgesic. Used in the treatment of urinary incontinence
[Definition]

ChEBI: (S,S)-tramadol hydrochloride is a hydrochloride resulting from the reaction of (S,S)-tramadol with 1 molar equivalent of hydrogen chloride; the (S,S)-enantiomer of the racemic opioid analgesic tramadol hydrochloride, it exhibits ten-fold lower analgesic potency than the (R,R)-enantiomer. It has a role as a delta-opioid receptor agonist, a kappa-opioid receptor agonist, a mu-opioid receptor agonist, an adrenergic uptake inhibitor, an antitussive, a capsaicin receptor antagonist, a muscarinic antagonist, a NMDA receptor antagonist, an opioid analgesic, a serotonergic antagonist and a serotonin uptake inhibitor. It contains a (S,S)-tramadol(1+). It is an enantiomer of a (R,R)-tramadol hydrochloride.
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