| Identification | Back Directory | [Name]
(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE | [CAS]
148700-85-0 | [Synonyms]
L 733060
L-733,060 hydrochlor
L-733,060 HYDROCHLORIDE
3-((3,5-Bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine
Piperidine, 3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenyl-, (2S,3S)-
(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE | [Molecular Formula]
C20H19F6NO | [MDL Number]
MFCD05865535 | [MOL File]
148700-85-0.mol | [Molecular Weight]
403.36 |
| Hazard Information | Back Directory | [Definition]
ChEBI: (2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine is a member of piperidines. | [Biological Activity]
A potent antagonist of human tachykinin NK 1 receptors (K i values are 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors respectively). Produces anxiolytic-like effects in the gerbil elevated plus-maze; orally bioavailable and brain penetrant. |
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