ChemicalBook--->CAS DataBase List--->148796-53-6

148796-53-6

148796-53-6 Structure

148796-53-6 Structure
IdentificationBack Directory
[Name]

ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID
[CAS]

148796-53-6
[Synonyms]

HFPA
HYDROXYFARNESYL PHOSPHATE
MONZTFSZTWQCKH-IJFRVEDASA-N
A-hydroxyfarnesylphosphonic acid
α-hydroxy Farnesyl Phosphonic Acid
alpha-Hydroxyfarnesylphosphonic aicd
ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID
ALPHA-HYDROXYFARNESYL PHOSPHONIC ACID ETHANOL SOLUTION
αhydroxy Farnesyl Phosphonic Acid,α hydroxy Farnesyl Phosphonic Acid
(+/-)-1-HYDROXY-3,7,11-TRIMETHYL-2E,6E,10-DODECATRIENE-1-PHOSPHONIC ACID
Phosphonic acid, P-[(2E,6E)-1-hydroxy-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-
[EINECS(EC#)]

200-578-6
[Molecular Formula]

C15H27O4P
[MDL Number]

MFCD00216148
[MOL File]

148796-53-6.mol
[Molecular Weight]

302.35
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

10 mM Na2CO3: freely soluble; ETOH: >25 mg/ml; PBS pH 7.2: <25 μg/ml
[form ]

A crystalline solid
Safety DataBack Directory
[Hazard Codes ]

F,Xi
[Risk Statements ]

11-36/37/38
[Safety Statements ]

16-26-36-7
[RIDADR ]

UN 1170 3/PG 2
[WGK Germany ]

3
Hazard InformationBack Directory
[Description]

α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations greater than 1 μM, α-hydroxy farnesyl phosphonic acid inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells.
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