| Identification | Back Directory | [Name]
Amino-PEG4-Val-Cit-PAB-MMAE | [CAS]
1492056-71-9 | [Synonyms]
Amino-PEG4-Val-Cit-PAB-MMAE
Amino-PEG4-Val-Cit-PAB-MMAE USP/EP/BP | [Molecular Formula]
C69H115N11O17 | [MDL Number]
MFCD32207022 | [Molecular Weight]
1370.71 |
| Questions And Answer | Back Directory | [Uses]
Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | [In Vitro]
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. MCE has not independently confirmed the accuracy of these methods. They are for reference only. | [Storage]
Please store the product under the recommended conditions in the Certificate of Analysis. |
| Chemical Properties | Back Directory | [Boiling point ]
1339.0±65.0 °C(Predicted) | [density ]
1.171±0.06 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DCM, DMF | [form ]
Solid | [pka]
13.29±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Amino-PEG4-Val-Cit-PAB-MMAE is a precursor of antibody drug conjugate. It contains an amino-PEG4 spacer, a protease-sensitive Val-Cit dipeptide, a PABC linker and a MMAE payload. It can be attached to a monoclonal antibody (MAB) which directs it toward cancer cells. |
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| Company Name: |
Abydos Scientific
|
| Tel: |
025-84767922 18936879710 |
| Website: |
http://www.abydoscientific.com/index.html |
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