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14944-34-4

14944-34-4 Structure

14944-34-4 Structure
IdentificationBack Directory
[Name]

6,7-(Epoxymethanoxy)-9-(1,3-benzodioxole-5-yl)-1,3-dihydronaphtho[2,3-c]furan-1-one
[CAS]

14944-34-4
[Synonyms]

Taiwanin C
5-(1,3-Benzodioxol-5-yl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(8H)-one
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(8H)-one, 5-(1,3-benzodioxol-5-yl)-
6,7-(Epoxymethanoxy)-9-(1,3-benzodioxole-5-yl)-1,3-dihydronaphtho[2,3-c]furan-1-one
[Molecular Formula]

C20H12O6
[MOL File]

14944-34-4.mol
[Molecular Weight]

348.31
Hazard InformationBack Directory
[Uses]

Taiwanin C selectively inhibits arecoline and 4-NQO-induced oral cancer cell proliferation via ERK1/2 inactivation.
[Definition]

ChEBI: Taiwanin C is a furonaphthodioxole that is furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one subtituted by a 1,3-benzodioxol-5-yl group at position 5. It is a naturally occurring lignan extracted from Taiwania cryptomerioides and found to be a potential inhibitor of COX2 expression. It has a role as a plant metabolite, an antineoplastic agent and a platelet aggregation inhibitor. It is a furonaphthodioxole, a member of benzodioxoles and a lignan.
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