| Identification | Back Directory | [Name]
m-PEG2-acid | [CAS]
149577-05-9 | [Synonyms]
mPEG2-COOH
mPEG1-COOH
m-PEG2-acid
m-dPEG2-acid
m-dPEG??-acid
MeOCH2CH2OCH2COOH
3-(2-Methoxyethoxy)propionic Acid
Propanoic acid, 3-(2-methoxyethoxy)- | [Molecular Formula]
C6H12O4 | [MDL Number]
MFCD09939037 | [MOL File]
149577-05-9.mol | [Molecular Weight]
148.16 |
| Chemical Properties | Back Directory | [Boiling point ]
244.2±20.0 °C(Predicted) | [density ]
1.098±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
Liquid | [pka]
4.28±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
m-PEG2-acid is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
m-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. | [Definition]
ChEBI:3-(2-methoxyethoxy)propanoic acid is a monocarboxylic acid that is propanoic acid substituted at C-3 by a 2-methoxyethoxy group. It has a role as a metabolite. It is a monocarboxylic acid and an ether. | [IC 50]
PEGs | [References]
[1] Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. DOI:10.3762/bjoc.11.74 |
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