Identification | Back Directory | [Name]
MMP-1/MMP-9 SUBSTRATE, FLUOROGENIC | [CAS]
150956-92-6 | [Synonyms]
MMP HPLC SUBSTRATE III Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 MMP-1/MMP-9 Fluorogenic Substrate MMP-1/MMP-9 SUBSTRATE, FLUOROGENIC DNP-P-CHA-G-C(ME)-HAK[ABZ(N-ME)]-NH2 DNP-PRO-CHA-GLY-CYS(ME)-HIS-ALA-LYS(NMA)-NH2 DNP-PRO-CHA-GLY-CYS(ME)-HIS-ALA-LYS[ABZ(N-ME)]-NH2 DNP-PRO-CHA-GLY-CYS(ME)-HIS-ALA-LYS(N-ME-2-ABZ)-NH2 Dnp-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-amide Dnp-Pro-β-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2 Dnp-Pro-b-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2 DNP-PRO-BETA-CYCLOHEXYL-ALA-GLY-CYS(ME)-HIS-ALA-LYS(N-ME-ABZ)-NH2 DNP-P-CHA-G-CYS(ME)-HA-K(NMA)-NH2;MMP-1/MMP-9 FLUOROGENIC SUBSTRATE L-Lysinamide, 1-(2,4-dinitrophenyl)-L-prolyl-3-cyclohexyl-L-alanylglycyl-S-methyl-L-cysteinyl-L-histidyl-L-alanyl-N6-[2-(methylamino)benzoyl]- (9CI) (2S)-N-[(2S)-1-[[2-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-6-[[2-(methylamino)benzoyl]amino]-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methylsulfanyl-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-cyclohexyl-1-oxopropan-2-yl]-1-(2,4-dinitrophenyl)pyrrolidine-2-carboxamide | [Molecular Formula]
C49H68N14O12S | [MDL Number]
MFCD00237630 | [MOL File]
150956-92-6.mol | [Molecular Weight]
1077.22 |
Chemical Properties | Back Directory | [Boiling point ]
1490.5±65.0 °C(Predicted) | [density ]
1.341±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Formic Acid: 1 mg/ml | [form ]
A lyophilized powder | [pka]
12.81±0.46(Predicted) |
Hazard Information | Back Directory | [Description]
Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9. Upon cleavage by MMP-1 or MMP-9, N-methylanthranilic acid (Nma) is unquenched and its fluorescence can be used to quantify MMP activity. Nma displays excitation/emission spectra of 340/440 nm, respectively. |
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