ChemicalBook--->CAS DataBase List--->150956-92-6

150956-92-6

150956-92-6 Structure

150956-92-6 Structure
IdentificationBack Directory
[Name]

MMP-1/MMP-9 SUBSTRATE, FLUOROGENIC
[CAS]

150956-92-6
[Synonyms]

MMP HPLC SUBSTRATE III
Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2
MMP-1/MMP-9 Fluorogenic Substrate
MMP-1/MMP-9 SUBSTRATE, FLUOROGENIC
DNP-P-CHA-G-C(ME)-HAK[ABZ(N-ME)]-NH2
DNP-PRO-CHA-GLY-CYS(ME)-HIS-ALA-LYS(NMA)-NH2
DNP-PRO-CHA-GLY-CYS(ME)-HIS-ALA-LYS[ABZ(N-ME)]-NH2
DNP-PRO-CHA-GLY-CYS(ME)-HIS-ALA-LYS(N-ME-2-ABZ)-NH2
Dnp-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-amide
Dnp-Pro-β-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2
Dnp-Pro-b-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2
DNP-PRO-BETA-CYCLOHEXYL-ALA-GLY-CYS(ME)-HIS-ALA-LYS(N-ME-ABZ)-NH2
DNP-P-CHA-G-CYS(ME)-HA-K(NMA)-NH2;MMP-1/MMP-9 FLUOROGENIC SUBSTRATE
L-Lysinamide, 1-(2,4-dinitrophenyl)-L-prolyl-3-cyclohexyl-L-alanylglycyl-S-methyl-L-cysteinyl-L-histidyl-L-alanyl-N6-[2-(methylamino)benzoyl]- (9CI)
(2S)-N-[(2S)-1-[[2-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-6-[[2-(methylamino)benzoyl]amino]-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methylsulfanyl-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-cyclohexyl-1-oxopropan-2-yl]-1-(2,4-dinitrophenyl)pyrrolidine-2-carboxamide
[Molecular Formula]

C49H68N14O12S
[MDL Number]

MFCD00237630
[MOL File]

150956-92-6.mol
[Molecular Weight]

1077.22
Chemical PropertiesBack Directory
[Boiling point ]

1490.5±65.0 °C(Predicted)
[density ]

1.341±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Formic Acid: 1 mg/ml
[form ]

A lyophilized powder
[pka]

12.81±0.46(Predicted)
Hazard InformationBack Directory
[Description]

Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9. Upon cleavage by MMP-1 or MMP-9, N-methylanthranilic acid (Nma) is unquenched and its fluorescence can be used to quantify MMP activity. Nma displays excitation/emission spectra of 340/440 nm, respectively.
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