| Identification | Back Directory | [Name]
2H-Pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one, 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-1,3,4,7-tetrahydro-8-(hydroxymethyl)-7-(phenylsulfonyl)- | [CAS]
1513860-41-7 | [Synonyms]
2H-Pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one, 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-1,3,4,7-tetrahydro-8-(hydroxymethyl)-7-(phenylsulfonyl)- | [Molecular Formula]
C26H24F2N4O6S | [MOL File]
1513860-41-7.mol | [Molecular Weight]
558.55 |
| Chemical Properties | Back Directory | [Boiling point ]
773.6±70.0 °C(Predicted) | [density ]
1.48±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, away from moisture and light | [form ]
Solid | [pka]
13.65±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Biological Activity]
FGFR-IN-1 is a potent FGFR inhibitor with an IC50 of <100 nM for FGFR1, FGFR2, and FGFR3, respectively (patent US20130338134A1, example 219)[1]. | [storage]
4°C, away from moisture and light | [References]
[1]. Liangxing Wu, et al. Substituted tricyclic compounds as fgfr inhibitors. US20130338134A1. |
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