| Identification | Back Directory | [Name]
Vinrosidine | [CAS]
15228-71-4 | [Synonyms]
Vinrosidine
Leurosidine
Leurosidine diacetate
Vinrosidine diacetate
(4'R)-Vincaleukoblastine
Vincaleukoblastine, (4'α)-
(2'S,4'R)-Vincaleukoblastine | [Molecular Formula]
C46H58N4O9 | [MDL Number]
MFCD01716247 | [MOL File]
15228-71-4.mol | [Molecular Weight]
810.983 |
| Hazard Information | Back Directory | [Description]
Also obtained from Vinca rosea L., this alkaloid is dextrorotatory with [α]25D + 55.8° (CHCI3). There are two absorption maxima in the ultraviolet spectrum at
214 and 265 mfJ.. A crystalline O,O,N-triacetyl derivative has been prepared with
m.p. 154-9°C (dec.); [α]25D + 12.6° (CHCl3). Two of the nitrogen atoms are
tertiary, the others being present as an imino and a methylimino group respec?
tively. The structure has been established from chemical | [Uses]
Antineoplastic. | [References]
Svoboda., Lloydia, 24, 173 (1961)
Structure:
Neuss, Huckstep, Cone., Tetrahedron Lett., 811 (1967) |
|
|