| Identification | Back Directory | [Name]
(S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one | [CAS]
1523404-29-6 | [Synonyms]
129208
Vps34-IN-2
Vps34 inhibitor 2
Vps-34-IN-2,Vps34 IN 2,Vps34IN2
(S)-1-(3-Methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyri
(S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one
(S)-9-(3-Methyl-2-oxobutyl)-2-((R)-3-methylmorpholino)-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one
(8S)-6,7,8,9-Tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-9-(3-methyl-2-oxobutyl)-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one
4H-Pyrimido[1,2-a]pyrimidin-4-one, 6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-9-(3-methyl-2-oxobutyl)-8-(trifluoromethyl)-, (8S)- | [Molecular Formula]
C18H25F3N4O3 | [MDL Number]
MFCD28411355 | [MOL File]
1523404-29-6.mol | [Molecular Weight]
402.41 |
| Chemical Properties | Back Directory | [Boiling point ]
466.4±55.0 °C(Predicted) | [density ]
1.40±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Ethanol: 50 mg/mL (124.25 mM) | [form ]
Solid | [pka]
0.08±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
(8S)-6,7,8,9-Tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-9-(3-methyl-2-oxobutyl)-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one, is a novel, potent and selective inhibitor of Vps34 with IC50s of 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively. |
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