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153463-21-9

153463-21-9 Structure

153463-21-9 Structure
IdentificationBack Directory
[Name]

25,26,26,26,27,27,27-heptafluorocholesterol
[CAS]

153463-21-9
[Synonyms]

F7-Cholesterol
25,26,26,26,27,27,27-heptafluorocholesterol
25,26,26,26,27,27,27-HEPTAFLUOROCHOLESTEROL;F7-CHOLESTEROL
Cholest-5-en-3-ol, 25,26,26,26,27,27,27-heptafluoro-, (3β)-
[Molecular Formula]

C27H39F7O
[MDL Number]

MFCD28143665
[MOL File]

153463-21-9.mol
[Molecular Weight]

512.59
Chemical PropertiesBack Directory
[Boiling point ]

465.8±40.0 °C(Predicted)
[density ]

1.20±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[pka]

15.03±0.70(Predicted)
[EPA Substance Registry System]

(3.beta.)-25,26,26,26,27,27,27-Heptafluoro-cholest-5-en-3-ol (153463-21-9)
Hazard InformationBack Directory
[Uses]

F7-Cholesterol has been used:
  • in the preparation of liposomes for DNA delivery studies
  • to investigate its rescue functionality in hedgehog signaling in sterol-depleted cells
  • in preparation of monolayers for pressure and area isotherms studies

[General Description]

F7-Cholesterol is a fluorinated derivative of cholesterol. It is a cholesterol analog. F7-Cholesterol is useful as helper lipid in conjunction with vectors for DNA transfection.
[Biochem/physiol Actions]

F7-Cholesterol has potential biological applications. It has a negative dipole moment. F7-Cholesterol rescues hedgehog signaling in sterol-depleted cells. The molecular orientation and phospholipid interaction of F7-cholesterol is similar to hydrogenated cholesterol.
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