Identification | Back Directory | [Name]
25,26,26,26,27,27,27-heptafluorocholesterol | [CAS]
153463-21-9 | [Synonyms]
F7-Cholesterol 25,26,26,26,27,27,27-heptafluorocholesterol 25,26,26,26,27,27,27-HEPTAFLUOROCHOLESTEROL;F7-CHOLESTEROL Cholest-5-en-3-ol, 25,26,26,26,27,27,27-heptafluoro-, (3β)- | [Molecular Formula]
C27H39F7O | [MDL Number]
MFCD28143665 | [MOL File]
153463-21-9.mol | [Molecular Weight]
512.59 |
Hazard Information | Back Directory | [Uses]
F7-Cholesterol has been used:
- in the preparation of liposomes for DNA delivery studies
- to investigate its rescue functionality in hedgehog signaling in sterol-depleted cells
- in preparation of monolayers for pressure and area isotherms studies
| [General Description]
F7-Cholesterol is a fluorinated derivative of cholesterol. It is a cholesterol analog. F7-Cholesterol is useful as helper lipid in conjunction with vectors for DNA transfection. | [Biochem/physiol Actions]
F7-Cholesterol has potential biological applications. It has a negative dipole moment. F7-Cholesterol rescues hedgehog signaling in sterol-depleted cells. The molecular orientation and phospholipid interaction of F7-cholesterol is similar to hydrogenated cholesterol. |
|
Company Name: |
Sigma-Aldrich
|
Tel: |
021-61415566 800-8193336 |
Website: |
https://www.sigmaaldrich.cn |
Company Name: |
Creative Enzymes
|
Tel: |
1-516-855-7709 |
Website: |
www.creative-enzymes.com |
|