ChemicalBook--->CAS DataBase List--->154130-99-1

154130-99-1

154130-99-1 Structure

154130-99-1 Structure
IdentificationBack Directory
[Name]

1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE
[CAS]

154130-99-1
[Synonyms]

PD 144418
PD 144418 OXALATE
Pyridine,1,2,3,6-tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propyl-
1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE
[Molecular Formula]

C18H22N2O
[MDL Number]

MFCD00924135
[MOL File]

154130-99-1.mol
[Molecular Weight]

282.38
Chemical PropertiesBack Directory
[storage temp. ]

Desiccate at RT
[solubility ]

<18.62mg/ml in DMSO
[form ]

solid
[color ]

Off-white
Hazard InformationBack Directory
[Uses]

PD 144418 is high affinity, selective σ1 ligand (Ki values are 0.08 and 1377 nM for σ1 and σ2 respectively). PD 144418 displays no significant activity at a wide range of other receptors, ion channels and enzymes. PD 144418 antagonizes mescaline-induced scratching in mice following i.p. administration.
[Biological Activity]

High affinity, selective σ 1 ligand (K i values are 0.08 and 1377 nM for σ 1 and σ 2 respectively). Displays no significant activity at a wide range of other receptors, ion channels and enzymes. Antagonizes mescaline-induced scratching in mice following i.p. administration.
[storage]

Desiccate at RT
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