| Identification | Back Directory | [Name]
annetocin | [CAS]
154445-03-1 | [Synonyms]
annetocin
Glycinamide, L-cysteinyl-L-phenylalanyl-L-valyl-L-arginyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-threonyl-, cyclic (1→6)-disulfide | [Molecular Formula]
C41H64N14O11S2 | [MOL File]
154445-03-1.mol | [Molecular Weight]
993.16 |
| Questions And Answer | Back Directory | [Structure]
Annetocin is composed of 9 aa residues containing
consensus aa in vertebrate OXT/VP family peptides:
Cys1, Asn5, Cys6, Pro7, Gly9, and C-terminal amidation. | [Target tissues and function]
The injection of annetocin into the earthworm resulted
in the induction of stereotypical egg-laying behavior.
Likewise, the injection of annetocin into the leech Whitmania
pigra leads to egg-laying behavior.Annetocin evokes
constructions of the nephridia and gut of the earthworm,
and the injection of annetocin into the leech induces the
reduction of body weight.Furthermore, another OXT/
VP superfamily peptide was isolated from a leech, Hirudo
verbana, and was named hirudotocin.The injection of hirudotocin into the leech induces a stereotypical twisting
that is instrumental to aligning gonopores in preparation
for copulation. |
| Hazard Information | Back Directory | [Description]
An oxytocin (OXT)/vasopressin (VP) superfamily peptide
was identified from the earthworm Eisenia foetida. The
injection of annetocin into the earthworm results in the
induction of stereotypical egg-laying behavior. |
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