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155204-09-4

155204-09-4 Structure

155204-09-4 Structure
IdentificationBack Directory
[Name]

(S)-Hydroxychloroquine sulfate
[CAS]

155204-09-4
[Synonyms]

(S)-Hydroxychloroquine sulfate
[Molecular Formula]

C18H28ClN3O5S
[MOL File]

155204-09-4.mol
[Molecular Weight]

433.95
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

DMSO: soluble,Methanol: soluble
[form ]

A solid
[Water Solubility ]

Water: soluble
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302+H312+H332-H315-H319
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P501
Hazard InformationBack Directory
[Biological Activity]

(S)-Hydroxychloroquine is an isomer of hydroxychloroquine .1 (S)-Hydroxychloroquine (2.5-20 mg/ml) reduces the rate of insulin degradation in isolated liver homogenates from non-diabetic and diabetic rats. Formulations containing hydroxychloroquine have been used in the prevention or treatment of malaria, as well as in the treatment of rheumatoid arthritis and systemic lupus erythematosus.
[storage]

-20°C
[References]

1.Emami, J., Pasutto, F.M., Mercer, J.R., et al.Inhibition of insulin metabolism by hydroxychloroquine and its enantiomers in cytosolic fraction of liver homogenates from healthy and diabetic ratsLife Sci.64(5)325-335(1999)
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