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15687-22-6

15687-22-6 Structure

15687-22-6 Structure
IdentificationBack Directory
[Name]

folescutol
[CAS]

15687-22-6
[Synonyms]

folescutol
6,7-Dihydroxy-4-(morpholinomethyl)-2H-1-benzopyran-2-one
2H-1-Benzopyran-2-one, 6,7-dihydroxy-4-(4-morpholinylmethyl)-
[EINECS(EC#)]

239-783-0
[Molecular Formula]

C14H15NO5
[MOL File]

15687-22-6.mol
[Molecular Weight]

277.27
Chemical PropertiesBack Directory
[Melting point ]

232°
[Boiling point ]

529.7±50.0 °C(Predicted)
[density ]

1.428±0.06 g/cm3(Predicted)
[pka]

7.80±0.20(Predicted)
Hazard InformationBack Directory
[Originator]

Folescutol ,hydrochloride
[Definition]

ChEBI: Folescutol is a hydroxycoumarin.
[Manufacturing Process]

A solution 35.6 g of 4-chlormethyl-6,7-dihydroxycoumarin and 27.3 g of morpholine in 4.5 L methyl ethyl ketone was refluxed for 9 hours. On cooling the morpholine hydrochloride was deleted. Methyl ethyl ketone was evaporated in vacuum. The solid product was mixed with 500 ml of water and dried in vacuum with P2O5. Yield of crude 6,7-dihydroxy-4(morpholinomethyl)coumarin is 41.5 g. After recrystallization from ethanol was obtained 6,7-dihydroxy-4-(morpholinomethyl)coumarin with M.P. 232°C.
In practice it is usually used as hydrochloride.
[Therapeutic Function]

Capillary protective
15687-22-6 suppliers list
Company Name: Lanospharma Laboratories Co.,Ltd  
Tel: 13440048448
Website: www.lanospharma.com
Company Name: Yick-Vic Chemicals & Pharmaceuticals (HK) Ltd  
Tel: (852)2541 2772
Website: www.yickvic.com
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