| Identification | Back Directory | [Name]
1,4-PBIT DIHYDROBROMIDE | [CAS]
157254-60-9 | [Synonyms]
1,4-PBIT DIHYDROBROMIDE
1,4-PB-ITU DIHYDROBROMIDE
YRRYHMLYGVNPBW-UHFFFAOYSA-N
1,4-Phenylene-bis(1,2-ethanediyl)bis-isothiourea dihydrobromide
S,S'-(1,4-PHENYLENE-BIS(1,2-ETHANEDIYL))BIS-ISOTHIOUREA DIHYDROBROMIDE | [Molecular Formula]
C12H20Br2N4S2 | [MDL Number]
MFCD00797677 | [MOL File]
157254-60-9.mol | [Molecular Weight]
444.25 |
| Chemical Properties | Back Directory | [Melting point ]
234-236 °C | [storage temp. ]
−20°C | [solubility ]
DMF: 20 mg/ml; DMSO: 25 mg/ml; PBS (pH 7.2): 5 mg/ml | [form ]
White to off-white powder. |
| Hazard Information | Back Directory | [Uses]
1,4-PBIT is a potent inhibitor of purified human iNOS and nNOS with Ki values of 7.4 and 16 nM, respectively, compared to a Ki of 360 nM for human eNOS. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability. | [storage]
Store at -20°C |
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SIGMA-RBI
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Alexis Corporation
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