ChemicalBook--->CAS DataBase List--->158930-17-7

158930-17-7

158930-17-7 Structure

158930-17-7 Structure
IdentificationBack Directory
[Name]

Frova
[CAS]

158930-17-7
[Synonyms]

Frova
Migard
Miguard
Frovelan
Unii-D28J6W18hy
Frovatriptan succinate [usan]
Frovatriptan succinate hydrate
Frovatriptan Succinate Monohydrate
(3R)-2,3,4,9-Tetrahydro-3-(methylamino)-1H-carbazole-6-carboxamide Butanedioic Acid Monohydrate
1H-Carbazole-6-carboxamide, 2,3,4,9-tetrahydro-3-(methylamino)-, (R)-, butanedioate (1:1), monohydrate
Butanedioic acid, compd. with (R)-2,3,4,9-tetrahydro-3-(methylamino)-1H-carbazole-6-carboxamide (1:1), monohydrate
[Molecular Formula]

C18H25N3O6
[MDL Number]

MFCD18251278
[MOL File]

158930-17-7.mol
Chemical PropertiesBack Directory
[Appearance]

White to Off-White Powder
[Melting point ]

150-153°C
[storage temp. ]

-20°C Freezer
[solubility ]

DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly, Heated)
[form ]

powder
[color ]

white to beige
[CAS DataBase Reference]

158930-17-7
Hazard InformationBack Directory
[Chemical Properties]

White to Off-White Powder
[Uses]

Serotonin 5-HT1B/1D receptor agonist. It is a triptan drug for the treatment of migraine headaches. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head
[Brand name]

Frova (Endo).
[Biochem/physiol Actions]

Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Frovatriptan has high affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower with a pEC50 value of 8.2 for the 5-HT1B receptor, compared to a pEC50 value of 6.2 for the 5-HT7 receptor.
[storage]

Store at -20°C
Safety DataBack Directory
[HS Code ]

2933995500
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