ChemicalBook--->CAS DataBase List--->159143-77-8

159143-77-8

159143-77-8 Structure

159143-77-8 Structure
IdentificationBack Directory
[Name]

3',5'-Dihydrodiol SiMvastatin (Mixture of DiastereoMers)
[CAS]

159143-77-8
[Synonyms]

Simvastatin Impurity 9
Simvastatin Impurity 15
Simvastatin Impurity 45
3',5'-Dihydrodiol SiMvastatin
(3S, 5S)-Dihydroxy Simvastatin
Simvastatin Dihydro Diol Impurity
3(s), 5(s)-Dihydroxy SiMvastatin-d3
[1S-[1α,3α,4β,6α,7β,8β(2S*,4S*),8aβ]]-
3',5'-Dihydrodiol SiMvastatin (Mixture of DiastereoMers)
Butanoic acid, 2,2-dimethyl-, 1,2,3,4,6,7,8,8a-octahydro-4,6-dihydroxy-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester, [1S-[1α,3α,4β,6α,7β,8β(2S*,4S*),8aβ]]- (9CI)
[Molecular Formula]

C25H40O7
[MOL File]

159143-77-8.mol
[Molecular Weight]

452.58
Chemical PropertiesBack Directory
[Melting point ]

65-85°C
[Boiling point ]

627.4±55.0 °C(Predicted)
[density ]

1.19±0.1 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

13.50±0.40(Predicted)
[color ]

White to Off-White
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

(3S,5S)-Dihydroxy Simvastatin is a derivtive of Simvastatin (S485000). Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.
[Uses]

A metabolite of Simvastatin (S485000).
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