ChemicalBook--->CAS DataBase List--->159752-10-0

159752-10-0

159752-10-0 Structure

159752-10-0 Structure
IdentificationBack Directory
[Name]

MK-677
[CAS]

159752-10-0
[Synonyms]

MK-667
CS-1402
MK-0667
nutrobal
Crescendo
IBUTAMORIN
MK677,Mk677
CHEMBL13817
MK-677 USP/EP/BP
Ibmoren mesylate
Ibutamoren Sarms
Ibumolan mesylate
Ibuprofen mesylate
MK-677(Ibutamoren)
Ibutamoren, MK-0677
MK-677,mk677,mk 677
Ibutamoren mesilate
MK677 MK 677 IBUTAMOREN
MK677 Ibutamoren mesilate
Pharmaceutical Grade MK677
MK677(Ibutamoren Mesylate)
MK-677(L163191,Ibutamoren)
Ibutamoren mesylate, >=98%
IbutaMoren Mesylate(MK-677)
MK 0677 Ibutamoren mesylate
MK-677 MK-677 White powder 99%
sarms mk 677 / mk677 ibutamoren
MK677(mesylate salt) Ibutamoren
MK677/MK-677/Ibutamoren Mesylate
Ibutamoren Mesylate/MK677/MK-677
MK677 (MK6, Nutrobal)-1 gram(31)
nicotinamide mononucleotide powder
Ibutamoren mesylate (MK-677) sarms
MK677 Synonyms: Ibutamoren Mesylate
MK-677,Ibutamoren Mesylate, nutrobal
High quality MK 677 sarms MK677 powder
mk677 mk 677 Ibutamoren,whnohe_lucy(at)163.com
MK677 MK-677 mk677 Sarms powder CAS NO.159752-10-0
MK-677; CRESCENDO; MK 0677; MK-0677; MK0677;MK677;MK 677
2-Amino-N-[2-benzyloxy-(1R)-[1-(methanesulfonyl)spiro[indoli...
2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-pip
China MK-677 mk 677 mk677 CAS 159752-10-0 supplier CAS NO. 159752-10-0
SARMs MK-677 Fat Burning Steroids CAS 159752-10-0 Ibutamoren For Muscle Gain
MK-677 Selective Androgen Receptor Modulators SARMs Bodybuilding CAS 159752-10-0
(R)-2-Amino-N-(3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidine]-1'-yl)-1-oxo
(R)-1'-(2-Methylalanyl-O-benzyl-D-seryl)-1-(Methylsulfonyl)-1,2-dihydrospiro[indole-3,4'-piperidine] Mesylate
MK 0677,MK 677,Inhibitor,Ibutamoren,MK677,inhibit,Ibutamoren Mesylate,Growth hormone secretagogue receptor,GHSR,MK0677
2-Amino-N-[2-benzyloxy-(1R)-[1-(methanesulfonyl)spiro[indoline-3,4'-piperidin]-1'-ylcarbonyl]ethyl]isobutyramide methanesulfonate
(R)-2-amino-N-(3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin]-1'-yl)-1-oxopropan-2-yl)-2-methylpropanamide methanesulfonate
2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide,methanesulfonicaci
2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide,methanesulfonic acid
N-[1(R)-1,2-Dihydro-1-methanesulfonylspiro-3H-indole-3,4′-piperidin)-1′-yl]carbonyl-2-(phenylmethoxy)-ethyl-2-amino-2-methylpropanamide methanesulfonate
2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide methanesulfonate
Propanamide, 2-amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methyl-, methanesulfonate (1:1)
[EINECS(EC#)]

1308068-626-2
[Molecular Formula]

C27H36N4O5S.CH4O3S
[MDL Number]

MFCD00942284
[MOL File]

159752-10-0.mol
[Molecular Weight]

624.776
Questions And AnswerBack Directory
[Description]

MK-677 (also known as ibutamoren), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1). Ibutamoren increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain. Clinical studies describe only the effects ibutamoren has on appetite and as expected, like ghrelin, ibutamoren increases it. GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition.
[Benefits]

The benefits of MK-677 include muscle-building, a reduction in muscle wasting, better bone density, improved sleep, and anti-aging properties. It may also have nootropic effects and it can be beneficial in treating growth hormone deficiencies. 
Chemical PropertiesBack Directory
[Melting point ]

164-170°C
[storage temp. ]

2-8°C
[solubility ]

H2O: soluble5mg/mL, clear
[form ]

powder
[color ]

white to beige
[InChIKey]

DUGMCDWNXXFHDE-VZYDHVRKSA-N
[SMILES]

S(O)(=O)(=O)C.S(N1C2C=CC=CC=2C2(CCN(C(=O)[C@H](NC(=O)C(N)(C)C)COCC3C=CC=CC=3)CC2)C1)(=O)(=O)C |&1:19,r|
Safety DataBack Directory
[WGK Germany ]

3
[RTECS ]

TX1404490
Hazard InformationBack Directory
[Uses]

Growth hormone releasing factor.
[Biochem/physiol Actions]

It is also known as ibutamoren mesylate. MK-677 is a mimic of growth hormone (GH)-releasing peptide and is orally active.
[Side effects]

Reported side effects of MK-677 are typically the result of unnaturally high levels of growth hormone in the body from taking too much too often, which include:
Increased appetite
Lethargy
Joint pain if you have previous medical conditions or elevated hormone levels
Insulin resistance
Possible increase in prolactin levels, which can be controlled
When dosed properly, the side effects of MK-677 are minimal to none compared to the results you get from taking it properly. 
[storage]

Store at -20°C
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