| Identification | Back Directory | [Name]
BW 723C86 | [CAS]
160521-72-2 | [Synonyms]
BW 723C8
BW 723C86
BW723C86HCl
Zinc02379519
BW 723C86 hydrochlor
BW-723C86
(BW 723C86
BW 723C86 HYDROCHLORIDE
A-Methyl-5-(2-Thienylmethox
BW 723C86 \ 5-HT2B SEROTONIN RECEPTOR AG ONIST
a-methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanaminehydrochloride
α-methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanaminehydrochloride
1-(5-(Thiophen-2-ylmethoxy)-1H-indol-3-yl)propan-2-amine hydrochloride
α-Methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanamine Monohydrochloride
a-Methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanamine Monohydrochloride
ALPHA-METHYL-5-(2-THIENYLMETHOXY)-1H-INDOLE-3-ETHANAMINE HYDROCHLORIDE
ALPHA-METHYL-5-(2-THIENYLMETHOXY)-1H-INDOLE-3-ETHANAMINE, MONOHYDROCHLORIDE
Α-METHYL-5-(2-THIENYLMETHOXY)-1H-INDOLE-3-,ETHANAMINEMONOHYDROCHLORIDE(BW723C86) | [Molecular Formula]
C16H19ClN2OS | [MDL Number]
MFCD01321066 | [MOL File]
160521-72-2.mol | [Molecular Weight]
322.85 |
| Hazard Information | Back Directory | [Uses]
BW 723C86 is a selective 5-HT2B receptor agonist. It is used in the treatment of certain CNS disorders, in particular epilepsy, migraine and feeding disorders.
| [Biological Activity]
Selective 5-HT 2B receptor agonist. | [Biochem/physiol Actions]
5-HT2B serotonin receptor agonist. | [storage]
Store at -20°C | [References]
[1]. kennett ga, bright f, trail b, et al. effects of the 5-ht2b receptor agonist, bw 723c86, on three rat models of anxiety. br j pharmacol, 1996, 117(7): 1443-1448.
[2]. dergacheva o, wang x, kamendi h, et al. 5ht2 receptor activation facilitates p2x receptor mediated excitatory neurotransmission to cardiac vagal neurons in the nucleus ambiguus. neuropharmacology, 2008, 54(7): 1095-1102.
[3]. kennett ga, trail b, bright f. anxiolytic-like actions of bw 723c86 in the rat vogel conflict test are 5-ht2b receptor mediated. neuropharmacology, 1998, 37(12): 1603-1610.
[4]. urtikova n, berson n, van steenwinckel j, et al. antinociceptive effect of peripheral serotonin 5-ht2b receptor activation on neuropathic pain. pain, 2012, 153(6): 1320-1331. |
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