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1613286-58-0

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1613286-58-0 Structure

1613286-58-0 Structure
IdentificationBack Directory
[Name]

DuocarMycin MB
[CAS]

1613286-58-0
[Synonyms]

CS-1381
DuocarMycin MB
Carbamic acid, N-[2-[[(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-3H-benz[e]indol-3-yl]carbonyl]-1H-indol-6-yl]-, 1,1-dimethylethyl ester
[Molecular Formula]

C27H26ClN3O4
[MDL Number]

MFCD28968742
[MOL File]

1613286-58-0.mol
[Molecular Weight]

491.97
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
Hazard InformationBack Directory
[Description]

Duocarmycin MB is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MB can be used against multi-drug resistant cell lines.

[storage]

Store at -20°C
[References]

[1]. Searcey M. Duocarmycins--natures prodrugs• Curr Pharm Des. 2002;8(15):1375-89.
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