| Identification | Back Directory | [Name]
QLKKMIWGFNMQJQ-JZFYYOKZSA-N | [CAS]
1621369-73-0 | [Synonyms]
QLKKMIWGFNMQJQ-JZFYYOKZSA-N
17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide
17-trifluoromethylphenyl trinor Prostaglandin F2.alpha. ethyl amide
9α,11α,15S-trihydroxy-17-trifluoromethylphenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid, ethyl amide
5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]-1-penten-1-yl]cyclopentyl]-N-ethyl-, (5Z)- | [Molecular Formula]
C26H36F3NO4 | [MOL File]
1621369-73-0.mol | [Molecular Weight]
483.56 |
| Hazard Information | Back Directory | [Description]
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor Prostaglandin F2α (17-trifluoromethylphenyl trinor PGF2α) is an analog of PGF2α that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2α ethyl amide is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2α. Ethyl amides of PGs can serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid. |
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