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162256-50-0

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162256-50-0 Structure

162256-50-0 Structure
IdentificationBack Directory
[Name]

CI 1020
[CAS]

162256-50-0
[Synonyms]

CI 1020
PD 156707
3-(1,3-Benzodioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]-2(5H)-furanone
2(5H)-Furanone, 3-(1,3-benzodioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]-
[Molecular Formula]

C28H26O9
[MDL Number]

MFCD00867525
[MOL File]

162256-50-0.mol
[Molecular Weight]

506.5
Chemical PropertiesBack Directory
[storage temp. ]

Store at +4°C
[solubility ]

Soluble to 50 mM in DMSO
[form ]

Powder
Hazard InformationBack Directory
[Uses]

A novel endothelin-A receptor antagonist, in hypoxic pulmonary hypertension.
[Biological Activity]

Highly selective, orally active, non-peptide endothelin-A receptor (ET A ) antagonist (IC 50 values are 0.3 and 480 nM for ET A and ET B receptors respectively). Antihypertensive; blocks ET-1-induced pressor responses following oral administration.
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