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162408-66-4

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162408-66-4 Structure

162408-66-4 Structure
IdentificationBack Directory
[Name]

4'-ACETYL-N-[4-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]BUTYL]-[1,1'-BIPHENYL]-4-CARBOXAMIDE
[CAS]

162408-66-4
[Synonyms]

GR 103691
4'-acetyl-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-[1,1'-biphenyl]-4-carboxamide
4'-ACETYL-N-[4-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]BUTYL]-[1,1'-BIPHENYL]-4-CARBOXAMIDE
[1,1'-Biphenyl]-4-carboxamide, 4'-acetyl-N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-
[Molecular Formula]

C30H35N3O3
[MDL Number]

MFCD00936840
[MOL File]

162408-66-4.mol
[Molecular Weight]

485.62
Chemical PropertiesBack Directory
[density ]

1.132
[storage temp. ]

2-8°C
[solubility ]

DMSO: ~9 mg/mL at 60 °C, soluble
[form ]

solid
[color ]

white
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

GR 103691 is a potent and selective receptor antagonist for D3DR.
[Definition]

ChEBI: 4-(4-acetylphenyl)-N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]benzamide is an aromatic ketone.
[Biological Activity]

A potent and selective dopamine D 3 receptor antagonist, with a K i value of 0.3 nM? and > 100- fold selectivity over D 2 and D 4 sites.
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