Identification | Back Directory | [Name]
Benzenesulfonamide, 5-chloro-2-fluoro-N-[4-[4-[(trans-4-hydroxycyclohexyl)oxy]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]- | [CAS]
1628048-93-0 | [Synonyms]
SGK1-IN-4 SGK1-IN-4 (compound 17a) Benzenesulfonamide, 5-chloro-2-fluoro-N-[4-[4-[(trans-4-hydroxycyclohexyl)oxy]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]- | [Molecular Formula]
C23H21ClFN5O4S | [MOL File]
1628048-93-0.mol | [Molecular Weight]
517.96 |
Hazard Information | Back Directory | [Biological Activity]
SGK1-IN-4 (compound 17a) is a highly selective, orally active SGK1 inhibitor. SGK1-IN-4 can be used for osteoarthritis research[1]. | [References]
[1]. Nis Halland, et al. Rational Design of Highly Potent, Selective, and Bioavailable SGK1 Protein Kinase Inhibitors for the Treatment of Osteoarthritis. J Med Chem. 2022 Jan 27;65(2):1567-1584. |
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