| Identification | Back Directory | [Name]
Amgen IRE1α Inhibitor | [CAS]
1630086-20-2 | [Synonyms]
Kira8
KIRA8 (AMG-18)
IRE-1 INHIBITOR
Amgen IRE1α Inhibitor
Benzenesulfonamide, 2-chloro-N-[6-methyl-5-[[3-[2-[(3S)-3-piperidinylamino]-4-pyrimidinyl]-2-pyridinyl]oxy]-1-naphthalenyl]- | [Molecular Formula]
C31H29ClN6O3S | [MDL Number]
MFCD28404657 | [MOL File]
1630086-20-2.mol | [Molecular Weight]
601.12 |
| Chemical Properties | Back Directory | [Boiling point ]
812.6±75.0 °C(Predicted) | [density ]
1.383±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Water:30.0(Max Conc. mg/mL);49.91(Max Conc. mM) | [form ]
Solid | [pka]
7.66±0.30(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Amgen IRE1α Inhibitor is an inhibitor of IRE1α. IRE1α is a sensor of unfolded protein accumulation that triggers the unfolded protein response. |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
|