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1631164-24-3

1631164-24-3 Structure

1631164-24-3 Structure
IdentificationBack Directory
[Name]

BAY-784
[CAS]

1631164-24-3
[Synonyms]

BAY-784
BAY1214784
[Molecular Formula]

C29H26ClF4N3O5S2
[MDL Number]

MFCD33023445
[MOL File]

1631164-24-3.mol
[Molecular Weight]

672.11
Chemical PropertiesBack Directory
[density ]

1.60±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: 2mg/mL, clear
[form ]

powder
[pka]

12.47±0.40(Predicted)
[color ]

white to beige
[optical activity]

[α]/D -120 to -100°, c =0.5 in chloroform-d
Hazard InformationBack Directory
[Biological Activity]

BAY-784 is an orally availablenon-toxicpotentand selective antagonist of human Gonadotropin-Releasing Hormone Receptor [hGnRH-R]which is potently active in other species including ratedogs and cynomolgus monkey. It partially lowered plasma luteinizing hormone levels in humans. BAY-784 exhibits favorable drug metabolism and pharmacokinetic (DMPK) profile thus is suitable for in vivo studies.
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