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163163-24-4

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163163-24-4 Structure

163163-24-4 Structure
IdentificationBack Directory
[Name]

(-)-[3R,4S]-CHROMANOL 293B
[CAS]

163163-24-4
[Synonyms]

(-)-[3R
4S]-Chromanol 293B
(-)-Chromanol 293B
(-)-[3R,4S]-Chromano
(-)-[3R,4S]-CHROMANOL 293B
(-)-[3R,4S]-Chromanol 293B
Chromanol 293B [3R,4S]-(-)-
( ) Chromanol 293B,()Chromanol 293B
N-[(3R,4S)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-METHYLETHANESULFONAMIDE
Ethanesulfonamide, N-[(3R,4S)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl-
[Molecular Formula]

C15H20N2O4S
[MDL Number]

MFCD06798368
[MOL File]

163163-24-4.mol
[Molecular Weight]

324.4
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

DMSO: 18 mg/mL
[form ]

solid
[color ]

white
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

20/21/22
[Safety Statements ]

36/37-7/9
[WGK Germany ]

3
Hazard InformationBack Directory
[Definition]

ChEBI: Chromanol 293B is a 1-benzopyran.
[Biological Activity]

Enantiomer that selectively inhibits the slow component of delayed rectifier K + current (I Ks ). Block is use-dependent and 7-fold more potent than the (+)-(3S,4R) enantiomer (IC 50 values are 1.36 and 9.6 μ M respectively). Has negligible inhibitory action at hERG channels (IC 50 > 30 μ M).
[storage]

Store at RT
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