ChemicalBook--->CAS DataBase List--->1632250-49-7

1632250-49-7

1632250-49-7 Structure

1632250-49-7 Structure
IdentificationBack Directory
[Name]

PF-06446846
[CAS]

1632250-49-7
[Synonyms]

PF-6446846
PF-06446846
Threonine proteases,PF06446846,Inhibitor,80S ribosome,Selective,PF 06446846,Ser/Thr Protease,Serine proteases,Rat bone marrow,Huh7,inhibit,Serine endopeptidases,PF-06446846
[Molecular Formula]

C22H20ClN7O
[MDL Number]

MFCD32182630
[MOL File]

1632250-49-7.mol
[Molecular Weight]

433.89
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 87 mg/mL (200.51 mM);Ethanol: 87 mg/mL (200.51 mM)
[Water Solubility ]

Water: Insoluble
Hazard InformationBack Directory
[Definition]

ChEBI: PF-06446846 is a triazolopyridine that is 3H-[1,2,3]triazolo[4,5-b]pyridine substituted by a 4-{(3-chloropyridin-2-yl)[(3R)-piperidin-3-yl]carbamoyl}phenyl group at position 3. It is a potent inhibitor of PCSK9. It has a role as an antilipemic drug and an EC 3.4.21.61 (kexin) inhibitor. It is a monochloropyridine, a member of piperidines, a tertiary carboxamide, a member of benzamides and a triazolopyridine.
Spectrum DetailBack Directory
[Spectrum Detail]

PF-06446846(1632250-49-7)1HNMR
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