| Identification | Back Directory | [Name]
Lu 28-179 | [CAS]
163630-79-3 | [Synonyms]
Lu 28-179
Siramesine (fumarate)
Siramesine fumarate salt
Siramesine fumarate salt >=98% (HPLC)
1′-[4-[1-(4-Fluorophenyl)indol-3-yl]butyl]spiro[1H-2-benzofuran-3,4′-piperidine] fumarate salt | [Molecular Formula]
C34H35FN2O5 | [MOL File]
163630-79-3.mol | [Molecular Weight]
570.66 |
| Hazard Information | Back Directory | [Biochem/physiol Actions]
Siramesine is a blood-brain barrier penetrant, selective and potent sigma-2 receptor agonist, which exhibits potent and very long-lasting anxiolytic effects in rodents. Also, siramesine is a lysosome-destabilizing agent that causes lysosomal cell death in varies immortalized and cancer cell lines. | [storage]
Store at -20°C |
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