| Identification | Back Directory | [Name]
N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite | [CAS]
163759-94-2 | [Synonyms]
2'-O-MOE-5-Me-C(Bz) Phosphoramidite
2'-O-MOE-5Me-C(Bz)-3'-phosphoramidite
5-Me-DMT-2'-O-MOE-C(Bz)-CE-Phosphoramidite
5'-O-DMT-2’-MOE-N6-Bz-5-Methycytidine-CE-Phosphoramidite
N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
N4-Bz-5'-O-DMTr-2'-O-(2-methoxyethyl)-5-methylcytidine-3'-CED-phosphoramidite
5'-O-DMT-N4-Acetyl-5-Methy-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite
5'-O-DMT-N4-Benzoyl-5-Methy-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite
N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl diisopropylphosphoramidite)
N4-benzoyl-5-methyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine-3'-cyanoethyl Phosphoramidite
5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-5-methyl-N4-benzoyl- cytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Cytidine, N-benzoyl-5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-(2-Methoxyethyl)-5-Methyl-, 3'-[2-cyanoethyl bis(1-Methylethyl)phosphoraMidite]
N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
N-[1-[(2R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide | [Molecular Formula]
C50H60N5O10P | [MDL Number]
MFCD00792624 | [MOL File]
163759-94-2.mol | [Molecular Weight]
922.01 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [form ]
Powder | [pka]
8.59±0.40(Predicted) | [color ]
White to Off-white | [InChIKey]
FLIGVMLIIDVDSN-SQULMOJWNA-N | [SMILES]
O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=C(C)C(NC(=O)C3=CC=CC=C3)=NC2=O)[C@H](OCCOC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,45,51,r| |
| Hazard Information | Back Directory | [Uses]
N4-Benzoyl-5''-O-DMT-2''-O-methylcytidine 3''-CE phosphoramidite (CAS# 163759-94-2) is a nucleotide used in the stereoselective synthesis of nucleoside alkyl-phosphonates. | [General Description]
DMT-2′O-MOE-rMeC(bz) Phosphoramidite (N4-Bz-5'-O-DMTr-2'-O-(2-methoxyethyl)-5-methylcytidine-3'-CED-phosphoramidite) is a phosphoramidite that belongs to the family of amides of trivalent phosphorus acid H3PO3. N4-Bz-5'-O-DMTr-2'-O-(2-methoxyethyl)-5-methylcytidine-3'-CED-phosphoramidite features a 2'-O-MOE group and can be incorporated into oligonucleotide phosphoramidites for antisense RNA. The 2'-MOE backbone enhances duplex stability, nuclease resistance, and has low toxicity. |
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