ChemicalBook--->CAS DataBase List--->1644158-57-5

1644158-57-5

1644158-57-5 Structure

1644158-57-5 Structure
IdentificationBack Directory
[Name]

Acid Ceramidase Inhibitor 17a
[CAS]

1644158-57-5
[Synonyms]

ARN14974
Acid Ceramidase Inhibitor 17a
6-(4-Fluorophenyl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3(2H)-carboxamide
[Molecular Formula]

C24H21FN2O3
[MDL Number]

MFCD32196894
[MOL File]

1644158-57-5.mol
[Molecular Weight]

404.43
Chemical PropertiesBack Directory
[density ]

1.276±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMF: 2 mg/ml; DMSO: 2 mg/ml
[form ]

A crystalline solid
[pka]

11.14±0.20(Predicted)
[color ]

Off-white to pink
Hazard InformationBack Directory
[Uses]

Acid Ceramidase Inhibitor 17a is a benzoxazolone carboxamide that potently inhibits acid cerimidase.
[Biological Activity]

Cell permeable: yes''Primary Target
Acid ceramidase''Reversible: no''Target IC50: 79 nM against HEK293 lysosomal lysate AC activity
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