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ChemicalBook--->CAS DataBase List--->1693734-80-3

1693734-80-3

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1693734-80-3 Structure

1693734-80-3 Structure
IdentificationBack Directory
[Name]

NPX809
[CAS]

1693734-80-3
[Synonyms]

NPX809
NPX800
NXP-800
[Molecular Formula]

C32H32FN5O4
[MOL File]

1693734-80-3.mol
[Molecular Weight]

569.63
Chemical PropertiesBack Directory
[Boiling point ]

612.2±55.0 °C(Predicted)
[density ]

1.347±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 100 mg/mL (175.55 mM; Need ultrasonic)
[form ]

Solid
[pka]

11.46±0.70(Predicted)
[color ]

Light yellow to green yellow
Hazard InformationBack Directory
[Biological Activity]

NXP800 (CCT361814) is a potent heat shock factor 1 (HSF1) inhibitor. NXP800 has the potential for cancer research[1]. NXP800 (example 169) inhibits U20S cells viability (IC50=0.056 μM)[1].
[References]

[1]. Keith Jones, et al. Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1. WO2015049535A1.
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