ChemicalBook--->CAS DataBase List--->169939-94-0

169939-94-0

169939-94-0 Structure

169939-94-0 Structure
IdentificationBack Directory
[Name]

RUBOXISTAURIN MESYLATE
[CAS]

169939-94-0
[Synonyms]

CS-1578
LY 333531
Ruboxistaurin
Unii-721809wqcp
LY 333531; LY 333531
RUBOXISTAURIN MESYLATE
Ruboxistaurin (LY333531)
Ruboxistaurin (LY333531) (HCl salt)
13-((Dimethylamino)methyl)-10,11,14,15-tetrahydro-4,9:16,21-dimetheno-1H,13H-dibenzo(E,K)pyrrolo(3,4-H)(1,4,13)oxadiazacyclohexadecene-1,3(2H)-dione
(S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione
9H,18H-5,21:12,17-Dimethenodibenzo(E,K)pyrrolo(3,4-H)(1,4,13)oxadiazacyclohexadecine-18,20(19H)-dione, 9-((dimethylamino)methyl)-6,7,10,11-tetrahydro-, (9S)-
[Molecular Formula]

C28H28N4O3
[MOL File]

169939-94-0.mol
[Molecular Weight]

468.55
Chemical PropertiesBack Directory
[Boiling point ]

744.4±60.0 °C(Predicted)
[density ]

1.34
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 50 mg/mL (106.71 mM; ultrasonic and warming and heat to 60°C)
[form ]

Solid
[pka]

8.26±0.40(Predicted)
[color ]

Brown to reddish brown
Hazard InformationBack Directory
[Uses]

Ruboxistaurin is a protein kinase C (PKC) β inhibitor, exhibits significant anti-angiogenic activity that reduces the response of vascular endothelial cells to stimulation by vascular endothelial growth factor (VEGF). Ruboxistaurin is used in treatment of diabetic microvascular complications.
[storage]

Store at -20°C
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