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ChemicalBook--->CAS DataBase List--->170856-41-4

170856-41-4

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170856-41-4 Structure

170856-41-4 Structure
IdentificationBack Directory
[Name]

PNU 96415E
[CAS]

170856-41-4
[Synonyms]

PNU 96415E
1-[2-(3,4-DIHYDRO-1H-2-BENZOPYRAN-1-YL)ETHYL]-4-(4-FLUOROPHENYL)PIPERAZINE DIHYDROCHLORIDE
[Molecular Formula]

C21H26ClFN2O
[MDL Number]

MFCD00940853
[MOL File]

170856-41-4.mol
[Molecular Weight]

376.9
Chemical PropertiesBack Directory
[storage temp. ]

Desiccate at RT
[form ]

Powder
[Water Solubility ]

Soluble to 10 mM in water
Hazard InformationBack Directory
[Uses]

PNU 96415E is an antipsychotic agent; SR-2A inhibitor.
[Biological Activity]

Antipsychotic agent. Displays high affinity for dopamine D 4 and serotonergic 5-HT 2A receptors and relatively weak affinity at D 2 receptors (K i values are 3.0, 5.8, 134, 181, 199, 240, 411 and > 678 nM for D 4 , 5-HT 2A , 5-HT 1A , α 1 , D 2 , D 3 , D 1 , α 2 ? and muscarinic receptors respectively). Inhibits exploratory locomotor activity and antagonizes d-amphetamine-induced locomotor stimulation in rats.
[storage]

Desiccate at RT
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