| Identification | Back Directory | [Name]
TAS 103 | [CAS]
174634-08-3 | [Synonyms]
TAS 103
CS-1287
BMS-247615
TAS-103 HC1
TAS-103 base
TAS-103(salt)
TA103(bms-247615)
6-[[2-(Dimethylamino)ethyl]amino]-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one
7H-Indeno[2,1-c]quinolin-7-one, 6-[[2-(dimethylamino)ethyl]amino]-3-hydroxy- | [Molecular Formula]
C20H19N3O2 | [MDL Number]
MFCD26960891 | [MOL File]
174634-08-3.mol | [Molecular Weight]
333.38 |
| Chemical Properties | Back Directory | [Melting point ]
216-217 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
589.5±50.0 °C(Predicted) | [density ]
1.350±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
7.88±0.20(Predicted) |
| Hazard Information | Back Directory | [Biological Activity]
TAS-103 is a dual DNA topoisomerase I/II (topoisomerase I/II) inhibitor for cancer research. | [in vivo]
TAS-103 (30 mg/kg, iv) causes significant tumor growth suppression in mice bearing Lewis lung carcinoma (LLC) cells, without obvious body weight loss, and the liposomal TAS-103 is more active than free TAS-103. | [target]
| Topoisomerase I | Topoisomerase II | | [storage]
Store at -20°C |
|
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
|